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Study of an inducible lysis device in E. coli
(1)Dipartimento di Informatica e Sistemistica, Università degli Studi di Pavia, Italy; (2) Centro di Ingegneria Tissutale, Università degli Studi di Pavia, Italy
In synthetic biological systems, cell lysis can be used to engineer programmed cell death and also to release proteins in extra-cellular environment, when secretion is not feasible. In this work, a promoterless lysis device called BBa_K112808, present in the Registry of Standard Biological Parts, was studied. A 3OC6-HSL inducible promoter was cloned upstream of the lysis device and used to characterize it.
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Validation of a standard approach for quantitative characterization of promoter strength
(1)Dipartimento di Informatica e Sistemistica, Università degli Studi di Pavia, Italy ; (2)Centro di Ingegneria Tissutale, Università degli Studi di Pavia, Italy
The rational design of synthetic biological systems can be performed only using a set of well-characterized biological parts. In this work, the Relative Promoter Units (RPUs) standard measurement method, proposed by Kelly et al., 2008, was validated and applied to characterize eight promoters from the Registry of Standard Biological Parts. The RPU approach allows the measurement of a promoter of interest using BBa_J23101 constitutive promoter as a standard reference.
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Compound Management Technologist, St Jude Children's Research Hospital, Memphis, TN
St. Jude Children's Research Hospital, located in Memphis, Tennessee, is a premier center for research and treatment of potentially fatal childhood diseases, including cancer and certain blood, genetic, and immunodeficiency disorders. The hospital's mission is to advance cures, and means of prevention, for pediatric catastrophic diseases through research and treatment. St. Jude is dedicated to providing unsurpassed patient care and to advancing the health of children through biomedical research.
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Postdoctoral Research Associate
Northeastern University
The Center for Drug Discovery at Northeastern University is dedicated to designing and discovering novel medications, developing technologies, and training scientists in the multidisciplinary field of drug discovery. We are recruiting a Postdoctoral Research Associate with expertise in protein-based mass spectrometry and /or proteomics.
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Product Manager - Techne, Stone, Staffordshire
Bibby Scientific
Bibby Scientific Ltd is one of the world’s leading manufacturers of Laboratory bench-top scientific equipment. For more information about the company, please visit their website (www.bibby-scientific.com).
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Assistant/Associate Professors
Chinese University of Hong Kong
The newly established School of Biomedical Sciences, Stem Cell and Regeneration theme is actively looking for stem cell biologist over the next 2 years.
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Macromolecular X-ray Crystallgrapher
Xtal Biostructures
Ph.D. Protein Crystallographer: We seek an experienced crystallographer with post-doctoral experience to participate in a number of our diverse structural biology activities.
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Marketing Communications Specialist Position in San Jose, CA
Thermo Fisher Scientific
This position, based in San Jose, CA within the SID Division, will manage promotion of Thermo Scientific mass spectrometry products and services.
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A global abstract analysis of selected histone-modifying enzymes using AKS
Active Motif
A global abstract analysis (GAA) was performed on twelve histone-modifying enzymes (ASH1, CARM1, CBP, CKII, EZH2, MSK1, MST1, NSD1, PCAF, RIZ1, SIRT2 and TIP60) to demonstrate how this approach can help uncover biological relationships, scientific information, and overall publication trends from PubMed abstracts and related biological databases. This GAA study showed that published research of histone-modifying enzymes has increased significantly since 2001 and that many reported studies have fo
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Multiplexed Diagnostics 2009 Market Report
Multiplexed diagnostics are the long-awaited ascendance of ’omics into healthcare. The promise of multiple measurements to characterize complexity is finally being realized.
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Cancer Personalized Medicine 2008
The Cancer Personalized Medicine marketplace represents the paradigm for personalized medicine market evolution and Select Biosciences focuses in this report on the various commercialized cancer predictor tests, their current status, traction in the marketplace, quantitative market opportunities, and the factors that are driving as well as challenging the expansion of this space. Personalized Medicine, especially as it relates to Cancer, is undergoing significant growth and this report focuses i
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